The Arthur and Sonia Labatt Brain Tumor Research Centre
Department of Pediatrics
University of Toronto
Toronto, Ontario, Canada
Dr. Huang received her PhD and MD degrees from the University of Toronto. Following residency training in Medical Genetics and Pediatrics at The Hospital for Sick Children in Toronto, she completed fellowship training in Pediatric Hematology/Oncology at The Hospital for Sick Children and a post-doctoral fellowship at the Ontario Cancer Institute, Princess Margaret Hospital. Dr. Huang was appointed to the Pediatric Brain Tumor Program of The Hospital for Sick Children in Toronto in July, 2002 as a Clinician Scientist.
Her lab is interested in mechanisms that underlie progression in primitive neuroectodermal tumors (PNETs), the most common group of pediatric malignant brain tumors. Due to the devastating consequences on the developing brain of the best current treatment, which includes radiation, there is much interest in uncovering molecular pathways that specify aggressive behavior in PNETs in order to ultimately develop more effective and less toxic treatments for such tumors. Current research focuses in part on the role of c-Myc, a potent oncoprotein, in specifying aggressive behavior in PNETs.